Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821405 | 0.86 | HPGD (0.69) | HPGDUPP1MEN1KMT2ADAO | |
| SCHEMBL7833489 | 0.82 | HPGD (0.64) | HPGDUPP1MEN1KMT2ADAO | |
| SCHEMBL7821453 | 0.82 | HPGD (0.64) | HPGDUPP1MEN1KMT2ADAO | |
| SCHEMBL24495513 | 0.81 | DAO (0.72) | HPGDMEN1KMT2ADAOMAPK1 | |
| SCHEMBL13932148 | 0.80 | HPGD (0.61) | HPGDUPP1MEN1KMT2ADAO | |
| SCHEMBL1717207 | 0.78 | MEN1 (0.78) | HPGDMEN1KMT2ADAO | |
| SCHEMBL5115615 | 0.78 | HPGD (0.67) | HPGDMEN1KMT2ADAOMAPK1 | |
| SCHEMBL4172709 | 0.78 | HPGD (0.67) | HPGDMEN1KMT2ADAOMAPK1 | |
| SCHEMBL3996660 | 0.78 | HPGD (1.00) | HPGDMAPK1 | |
| SCHEMBL11315735 | 0.76 | HPGD (0.65) | HPGDMEN1KMT2ADAOMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324436-A1 | METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2021-10-21 | — | — | US | disclosed |