SCHEMBL23934945

SCHEMBL23934945

CN1c2ccccc2C(C)(C)C12C=Nc1c(cc(N3CCCC3)c3ccccc13)O2

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.85
KDM4E B2RXH2 6/20 0.85
LMNA P02545 6/20 0.85
THRB P10828 4/20 0.85
NPSR1 Q6W5P4 3/20 0.85
CYP3A4 P08684 1/20 0.85
CYP2C9 P11712 1/20 0.85
CYP2C19 P33261 1/20 0.85
BLM P54132 1/20 0.85
SMN1; SMN2 Q16637 5/20 0.64
ALOX12 P18054 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
PKM P14618 1/20 0.64
ALDH1A1 P00352 6/20 0.56
GAA P10253 3/20 0.56
HPGD P15428 2/20 0.56
HTT P42858 2/20 0.56
RECQL P46063 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2398584 0.99 MAPT (0.83) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL10420416 0.99 MAPT (0.83) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL29968632 0.99 MAPT (0.83) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL10420938 0.93 MAPT (0.83) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL10419566 0.92 MAPT (1.00) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL13659154 0.91 MAPT (0.80) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL31127602 0.91 MAPT (0.80) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL9838567 0.91 MAPT (0.80) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL10420934 0.91 MAPT (0.84) MAPTKDM4ELMNATHRBNPSR1
SCHEMBL17342571 0.90 MAPT (0.69) MAPTKDM4ELMNATHRBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389619-A1 PHOTOCHROMIC THERMAL INSULATION FIBER AND MANUFACTURING METHOD THEREOF TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2022-12-08 US disclosed
EP-3901205-A1 PHOTOCHROMIC POLYPROPYLENE FIBER AND PREPARATION METHOD THEREOF Taiwan Textile Research Institute (TW) 2021-10-27 EP disclosed
US-20210324543-A1 PHOTOCHROMIC POLYPROPYLENE FIBER AND PREPARATION METHOD THEREOF TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2021-10-21 US disclosed