Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23935025 | 0.86 | LRRK2 (0.47) | LRRK2PDE10A | |
| SCHEMBL23935178 | 0.82 | LRRK2 (0.49) | LRRK2 | |
| SCHEMBL23935001 | 0.80 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL23935081 | 0.78 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL23935161 | 0.78 | LRRK2 (0.65) | LRRK2 | |
| SCHEMBL23935129 | 0.77 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL18623713 | 0.77 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL23935065 | 0.77 | LRRK2 (0.65) | LRRK2 | |
| SCHEMBL23935026 | 0.77 | LRRK2 (0.43) | LRRK2PDE10A | |
| SCHEMBL18659015 | 0.75 | LRRK2 (0.51) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350178-B1 | NOVEL IMIDAZO [4,5-C]QUINOLINE AND IMIDAZO [4,5-C][1,5]NAPHTHYRIDINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2021-10-20 | — | — | EP | disclosed |