SCHEMBL23935177

SCHEMBL23935177

c1ccc(-c2ccc3ccc4ccncc4c3c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 9/20 0.69
TNF P01375 1/20 0.56
PLG P00747 1/20 0.49
PLAU P00749 1/20 0.49
CYP19A1 P11511 2/20 0.49
CYP17A1 P05093 1/20 0.49
CYP11B1 P15538 1/20 0.49
CYP11B2 P19099 1/20 0.49
PRKCZ Q05513 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
HTT P42858 1/20 0.47
RAD52 P43351 1/20 0.47
MKNK1 Q9BUB5 1/20 0.46
PIK3CA P42336 1/20 0.45
NOTUM Q6P988 1/20 0.45
NCOA3 Q9Y6Q9 1/20 0.44
FGFR1 P11362 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22963498 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL22963212 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL22963611 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL22963264 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL22963628 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL22963215 0.84 MAPK10 (0.58) MAPK10TNFPLGPLAUCYP19A1
SCHEMBL27327157 0.82 MAPK10 (0.57) MAPK10TNFCYP11B1KDM4EPOLB
SCHEMBL3695546 0.82 ESR1 (0.54) PLGPLAUFGFR1
SCHEMBL30960425 0.82 ESR1 (0.54) PLGPLAUFGFR1
SCHEMBL22963413 0.81 MAPK10 (0.56) MAPK10TNFCYP19A1CYP17A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508472-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-10-20 EP disclosed