SCHEMBL23935948

SCHEMBL23935948

CC1(C)c2ccccc2-c2c(-c3ccc4c(-c5ccccc5)nc(-c5ccccc5)nc4c3)cccc2C1(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
WHR1 P49842 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
HPGD P15428 2/20 0.37
DHFR P00374 4/20 0.34
ADORA2A P29274 4/20 0.34
NUDT1 P36639 3/20 0.34
ADK P55263 2/20 0.34
ADORA1 P30542 2/20 0.33
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936024 0.92 WHR1 (0.45) WHR1MEN1KMT2AATMADORA2A
SCHEMBL18456041 0.91 WHR1 (0.44) WHR1MEN1KMT2AATMHPGD
SCHEMBL23936132 0.88 WHR1 (0.44) WHR1MEN1KMT2AATMHPGD
SCHEMBL18456047 0.87 MEN1 (0.45) WHR1MEN1KMT2AATMHPGD
SCHEMBL20465553 0.87 WHR1 (0.44) WHR1MEN1KMT2AATMHPGD
SCHEMBL23936492 0.86 MEN1 (0.49) WHR1MEN1KMT2AATMHPGD
SCHEMBL23936255 0.86 WHR1 (0.46) WHR1MEN1KMT2AATMHPGD
SCHEMBL23935966 0.85 MEN1 (0.46) WHR1MEN1KMT2AATMHPGD
SCHEMBL23936408 0.84 MEN1 (0.46) WHR1MEN1KMT2AATMHPGD
SCHEMBL18455633 0.84 WHR1 (0.39) WHR1MEN1KMT2AATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed