SCHEMBL23936668

SCHEMBL23936668

CC1(C)c2cc(N(c3ccccc3)c3ccc4c(c3)C(C)(C)C(C)(C)c3ccccc3-4)ccc2-c2cc3ccccc3cc21

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.40
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936871 0.95 PDK2 (0.39) PDK2KMT2A
SCHEMBL23936584 0.94 PDK2 (0.38) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL23936118 0.94 PDK2 (0.36) PDK2
SCHEMBL23936792 0.92 PDK2 (0.37) PDK2KMT2A
SCHEMBL16801581 0.92 PDK2 (0.40) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL21913805 0.91 PDK2 (0.41) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL23936104 0.90 PDK2 (0.42) PDK2KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL23936083 0.90 PDK2 (0.36) PDK2
SCHEMBL23936670 0.90 PDK2 (0.37) PDK2
SCHEMBL19197425 0.90 PDK2 (0.40) PDK2KDM4EALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed