SCHEMBL23936745

SCHEMBL23936745

CC1(C)c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2-c2ccc3c(ccc4ccccc43)c2C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.35
LMNA P02545 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
HPGD P15428 5/20 0.35
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 4/20 0.34
TSHR P16473 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPK1 P28482 3/20 0.34
ATM Q13315 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TP53 P04637 2/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936290 0.98 MAPT (0.34) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL23936494 0.96 MAPT (0.35) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL23936797 0.92 MAPT (0.36) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL23936363 0.89 MAPT (0.35) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL23936739 0.89 KDM4E (0.32) MAPTSMN1; SMN2KMT2AHPGDALDH1A1
SCHEMBL23936361 0.88 MAPT (0.35) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL26438330 0.88 MAPT (0.36) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL26438231 0.87 MAPT (0.36) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL23936509 0.85 MAPT (0.37) MAPTLMNASMN1; SMN2NPC1RECQL
SCHEMBL26438276 0.85 MAPT (0.36) MAPTLMNASMN1; SMN2NPC1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed