SCHEMBL23937671

SCHEMBL23937671

N#Cc1cccc2c1-c1ccc(-c3ccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc1C21c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.40
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 4/20 0.38
MAPT P10636 3/20 0.38
NTSR1 P30989 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
KDM4E B2RXH2 3/20 0.37
LMNA P02545 2/20 0.37
GLA P06280 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.36
MAOA P21397 3/20 0.34
MAOB P27338 3/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23937668 1.00 PDK2 (0.40) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937673 1.00 PDK2 (0.40) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937679 0.98 PDK2 (0.39) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937677 0.97 PDK2 (0.39) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937672 0.97 PDK2 (0.39) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937686 0.97 PDK2 (0.39) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937512 0.95 PDK2 (0.41) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937514 0.95 PDK2 (0.41) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937509 0.95 PDK2 (0.41) PDK2MEN1KMT2AALDH1A1HPGD
SCHEMBL23937358 0.95 PDK2 (0.38) PDK2MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896061-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Solus Advanced Materials Co., Ltd. (KR) 2021-10-20 EP disclosed