⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21704182 | 0.79 | — | — | |
| SCHEMBL21703986 | 0.78 | — | — | |
| SCHEMBL22249014 | 0.78 | — | — | |
| SCHEMBL23938183 | 0.68 | — | — | |
| SCHEMBL23938319 | 0.65 | KDM4E (0.32) | — | |
| SCHEMBL23938127 | 0.64 | — | — | |
| SCHEMBL23938266 | 0.62 | — | — | |
| SCHEMBL20731246 | 0.62 | SLC6A2 (0.37) | — | |
| SCHEMBL20732028 | 0.61 | — | — | |
| SCHEMBL18390361 | 0.61 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO EARLY DISCOVERY, INC. | 2021-10-21 | — | — | US | disclosed |