Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255844 | 0.84 | SRD5A1 (0.42) | SLC6A4SLC6A2SLC6A3HRH3SRD5A1 | |
| SCHEMBL18255846 | 0.84 | SRD5A1 (0.42) | SLC6A4SLC6A2SLC6A3HRH3SRD5A1 | |
| SCHEMBL18254950 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3HRH3SRD5A1 | |
| SCHEMBL18255842 | 0.84 | SRD5A1 (0.42) | SLC6A4SLC6A2SLC6A3HRH3SRD5A1 | |
| SCHEMBL23938535 | 0.83 | HTR2A (0.41) | HTR2AHTR2CHTR2BSRD5A1CA1 | |
| SCHEMBL5249380 | 0.81 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3HRH3CYP2D6 | |
| SCHEMBL18255841 | 0.81 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3HRH3SRD5A1 | |
| SCHEMBL2200079 | 0.76 | HTR2A (0.57) | HTR2AHTR2CHTR2BSRD5A1CA1 | |
| SCHEMBL2056192 | 0.74 | DPP7 (0.47) | HTR2AHTR2CHTR2BSRD5A1 | |
| SCHEMBL1248718 | 0.74 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297438-B1 | CCR2 MODULATORS | CHEMOCENTRYX INC (US) | 2021-10-20 | — | — | EP | disclosed |