Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281339 | 0.87 | CRBN (0.36) | DDB1CRBNKMT2AMEN1RAB9A | |
| SCHEMBL23939212 | 0.86 | CRBN (0.39) | DDB1CRBN | |
| SCHEMBL23939268 | 0.81 | DDB1 (0.42) | DDB1CRBNKMT2AMEN1 | |
| SCHEMBL21281540 | 0.79 | — | — | |
| SCHEMBL19309921 | 0.79 | CRBN (0.46) | DDB1CRBN | |
| SCHEMBL23939257 | 0.79 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL19310182 | 0.78 | CRBN (0.43) | DDB1CRBN | |
| SCHEMBL20459249 | 0.77 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL21924194 | 0.76 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL21927149 | 0.76 | CRBN (0.41) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643709-B1 | ISOINDOLINE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | KANGPU BIOPHARMACEUTICALS LTD (CN) | 2021-10-20 | — | — | EP | disclosed |