Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19672999 | 1.00 | RPS6KA1 (0.40) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL23939747 | 0.90 | RPS6KA1 (0.40) | RPS6KA1EPHX2KDM4ADRD2 | |
| SCHEMBL13035561 | 0.88 | RPS6KA1 (0.39) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL469384 | 0.88 | LARS1 (0.39) | RPS6KA1EPHX2KDM4AACACBGAA | |
| SCHEMBL469558 | 0.88 | LARS1 (0.39) | RPS6KA1EPHX2KDM4AACACBGAA | |
| SCHEMBL13035591 | 0.88 | RPS6KA1 (0.39) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL19647574 | 0.87 | RPS6KA1 (0.39) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL15077473 | 0.86 | RPS6KA1 (0.38) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL13035547 | 0.86 | RPS6KA1 (0.38) | RPS6KA1EPHX2KDM4ADRD2PCSK9 | |
| SCHEMBL13035541 | 0.85 | RPS6KA1 (0.38) | RPS6KA1EPHX2KDM4ADRD2PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251678-B1 | BENZOXABOROLE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | ANACOR PHARMACEUTICALS INC (US) | 2021-10-20 | — | — | EP | disclosed |