Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | ADA | P00813 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810522 | 1.00 | MEN1 (0.48) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL26202221 | 0.99 | ASAH1 (0.49) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL21559595 | 0.95 | ASAH1 (0.51) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL21388677 | 0.95 | ASAH1 (0.51) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL7854777 | 0.95 | ASAH1 (0.51) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL22810545 | 0.91 | MEN1 (0.48) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL22810547 | 0.87 | MEN1 (0.49) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL11414055 | 0.86 | MEN1 (0.51) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| Bromide SCHEMBL29283499 | 0.85 | MEN1 (0.50) | MEN1HPGDKMT2AHSD17B10ASAH1 | |
| SCHEMBL4558105 | 0.85 | ASAH1 (0.48) | MEN1HPGDKMT2AHSD17B10ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | TYK2, JAK3, JAK1 | MEN1 3877/4885HPGD 1814/4885KMT2A 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.