SCHEMBL23944874

SCHEMBL23944874

CCOc1ccc(Cc2cc(Cc3cc([C@H]4C[C@@H](O)[C@H](O)[C@@H](CO)O4)ccc3Cl)ccc2Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.68
SLC5A1 P13866 11/20 0.68
ADRA2A P08913 1/20 0.68
SLC5A11 Q8WWX8 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6342510 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19114776 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18736226 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18573712 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19429486 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19428703 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17189203 0.98 SLC5A2 (0.71) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL26816830 0.90 SLC5A2 (0.64) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13448994 0.90 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL27369066 0.89 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210323939-A1 NOVEL PROCESSES FOR PREPARATION OF DAPAGLIFLOZIN OR ITS SOLVATES OR CO-CRYSTALS THEREOF LAURUS LABS LIMITED (IN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323939-A1 NOVEL PROCESSES FOR PREPARATION OF DAPAGLIFLOZIN OR ITS SOLVATES OR CO-CRYSTALS THEREOF SLC5A1, SLC5A2, DPP4 SLC5A2 2/4885SLC5A1 1/4885ADRA2A 2269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.