Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25123484 | 0.94 | MEN1 (0.49) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL25704881 | 0.90 | MEN1 (0.50) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL25831763 | 0.87 | KMT2A (0.50) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL23696060 | 0.85 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL25706227 | 0.85 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL25466881 | 0.84 | MEN1 (0.53) | MEN1KMT2ATSHRGLP1RUSP2 | |
| SCHEMBL25827160 | 0.84 | MEN1 (0.53) | MEN1KMT2ATSHRGLP1RUSP2 | |
| SCHEMBL22375784 | 0.83 | MEN1 (0.49) | MEN1KMT2ATSHRGLP1RUSP2 | |
| SCHEMBL22861772 | 0.82 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL13857334 | 0.82 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | MEN1 4055/4885KMT2A 445/4885LMNA 1656/4885 |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | MEN1 4055/4885KMT2A 445/4885LMNA 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.