Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673499 | 0.87 | KDM4E (0.31) | PRMT6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23945375 | 0.86 | — | — | |
| SCHEMBL25727650 | 0.86 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24673798 | 0.86 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL25727661 | 0.84 | KDM4E (0.32) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25725942 | 0.84 | KDM4E (0.32) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23945883 | 0.83 | SLC2A1 (0.34) | — | |
| SCHEMBL24673755 | 0.82 | SLC2A1 (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24673804 | 0.82 | — | — | |
| SCHEMBL26018380 | 0.82 | SLC2A1 (0.33) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | CARM1 824/4885PRMT6 1616/4885PRMT8 1981/4885 |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CARM1 824/4885PRMT6 1616/4885PRMT8 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.