⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988204 | 0.67 | — | — | |
| SCHEMBL7631887 | 0.61 | — | — | |
| SCHEMBL15505319 | 0.58 | — | — | |
| SCHEMBL15505300 | 0.58 | — | — | |
| SCHEMBL31494129 | 0.58 | — | — | |
| SCHEMBL14129484 | 0.56 | — | — | |
| SCHEMBL8895904 | 0.53 | — | — | |
| SCHEMBL3233571 | 0.50 | DEPTOR (0.33) | — | |
| SCHEMBL10854454 | 0.50 | — | — | |
| SCHEMBL4662898 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934280-B1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-09 | — | — | EP | claimed |
| EP-0934280-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-08-11 | — | — | EP | claimed |
| WO-1998014432-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-04-09 | — | — | WO | claimed |
| US-20110223166-A1 | Methods for Preventing Pressure-Induced Apoptotic Neural-Cell Death | MINAS THEODORE CORONEO (AU) | 2011-09-15 | — | — | US | disclosed |
| US-7803760-B2 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20080293622-A1 | METHODS OF INDUCING OVULATION | MERCK SERONO SA (CH) | 2008-11-27 | — | — | US | disclosed |
| US-7364910-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2008-04-29 | — | — | US | disclosed |
| US-20060293222-A1 | METHODS OF INDUCING OVULATION | MERCK SERONO SA (CH) | 2006-12-28 | — | — | US | disclosed |
| US-7078236-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2006-07-18 | — | — | US | disclosed |
| US-20060013814-A1 | Methods for preventing pressure-induced apoptotic neural-cell death | DAVIES COLLISON CAVE (AU) | 2006-01-19 | — | — | US | disclosed |
| US-20060003925-A1 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2006-01-05 | — | — | US | disclosed |
| CN-1232456-A | PDE IV inhibiting 2-cyanoiminoimidazole derivs. | JANSSEN PHARMACEUTICA NV (BE) | 1999-10-20 | — | — | CN | disclosed |
| EP-0934280-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934280-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998014432-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-04-09 | — | — | WO | disclosed |
| WO-1998014432-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-04-09 | — | — | WO | disclosed |
| EP-0350805-B1 | Benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds | BEIERSDORF LILLY GMBH (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0350805-A1 | Benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds | Beiersdorf-Lilly GmbH (DE) | 1990-01-17 | — | — | EP | disclosed |