SCHEMBL23947296

SCHEMBL23947296

c1ccc(-c2nc(-c3ccc4oc5ccccc5c4c3)nc(-c3ccc4oc5cc(-c6cccc7c6c6ccccc6n7-c6ccccc6)ccc5c4c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
CHEK2 O96017 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
PRKDC P78527 1/20 0.33
MMP12 P39900 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGER4 P35408 1/20 0.32
HCRTR1 O43613 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
AHR P35869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947904 1.00 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL23947909 1.00 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL21192257 1.00 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL23947881 1.00 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL23947878 1.00 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL21192113 0.99 SIRT2 (0.34) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL22257885 0.99 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL22240935 0.99 SIRT2 (0.35) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL21192237 0.97 SIRT2 (0.36) SIRT2SIRT1CHEK2KDM4EATM
SCHEMBL21192250 0.97 KDM4E (0.36) SIRT2SIRT1KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, UBE2L3, OPRL1 SIRT2 924/4885SIRT1 1253/4885CHEK2 1929/4885
US-11873297-B2 Compound and organic light emitting device comprising the same CCNL2, UBE2L3, ARL1 SIRT2 875/4885SIRT1 1239/4885CHEK2 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.