⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500691 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL23466839 | 0.62 | — | — | |
| SCHEMBL24633930 | 0.62 | — | — | |
| SCHEMBL12462366 | 0.60 | — | — | |
| SCHEMBL23913519 | 0.60 | — | — | |
| SCHEMBL10098416 | 0.58 | — | — | |
| SCHEMBL24254047 | 0.58 | — | — | |
| SCHEMBL14384307 | 0.57 | DYRK1A (0.40) | — | |
| SCHEMBL23707839 | 0.57 | DYRK1A (0.30) | — | |
| SCHEMBL19589069 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211882-A1 | METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS | PYRAMID BIOSCIENCES, INC. (US) | 2021-10-21 | — | — | WO | disclosed |