Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.78 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.78 |
| ▸ | JAK2 | O60674 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148409 | 1.00 | NTRK1 (0.78) | NTRK1NTRK3JAK2 | |
| SCHEMBL23948284 | 1.00 | NTRK1 (0.78) | NTRK1NTRK3JAK2 | |
| SCHEMBL26305967 | 0.93 | NTRK1 (0.67) | NTRK1NTRK3JAK2 | |
| SCHEMBL26306035 | 0.93 | NTRK1 (0.67) | NTRK1NTRK3JAK2 | |
| SCHEMBL26305858 | 0.93 | NTRK1 (0.67) | NTRK1NTRK3JAK2 | |
| SCHEMBL26305999 | 0.92 | NTRK1 (0.65) | NTRK1NTRK3JAK2 | |
| SCHEMBL26305808 | 0.92 | NTRK1 (0.65) | NTRK1NTRK3JAK2 | |
| SCHEMBL26305909 | 0.92 | NTRK1 (0.65) | NTRK1NTRK3JAK2 | |
| SCHEMBL23948345 | 0.91 | NTRK1 (0.65) | NTRK1NTRK3JAK2 | |
| SCHEMBL23148347 | 0.91 | NTRK1 (0.65) | NTRK1NTRK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242536-A1 | METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS | PYRAMID BIOSCIENCES, INC. | 2023-08-03 | — | — | US | disclosed |
| WO-2021211882-A1 | METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS | PYRAMID BIOSCIENCES, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242536-A1 | METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS | LTK, FRK, LCK | NTRK1 5/4885NTRK3 27/4885JAK2 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.