Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | ERG | P11308 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 6/20 | 0.36 |
| ▸ | BRAF | P15056 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25568289 | 0.89 | AKT1 (0.37) | AKT1PPARGCCNCCDK8GPBAR1 | |
| SCHEMBL30257455 | 0.87 | AKT1 (0.43) | AKT1CCNCCDK8GPBAR1EGLN1 | |
| SCHEMBL25058669 | 0.87 | AKT1 (0.43) | AKT1CCNCCDK8GPBAR1EGLN1 | |
| SCHEMBL30257143 | 0.85 | PPARG (0.41) | AKT1PPARGEGLN1 | |
| SCHEMBL23949229 | 0.85 | PPARG (0.41) | AKT1PPARGEGLN1 | |
| SCHEMBL25555593 | 0.83 | PPARG (0.42) | AKT1PPARGEGLN1 | |
| SCHEMBL25567640 | 0.79 | AKT1 (0.37) | AKT1CCNCCDK8GPBAR1EGLN1 | |
| SCHEMBL23949944 | 0.77 | AKT1 (0.43) | AKT1CCNCCDK8GPBAR1ERG | |
| SCHEMBL30353355 | 0.77 | AKT1 (0.43) | AKT1CCNCCDK8GPBAR1ERG | |
| SCHEMBL25556285 | 0.75 | CCNC (0.39) | CCNCCDK8CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021210650-A1 | ARYL OR HETEROARYL DERIVATIVE | 帝人ファーマ株式会社 | 2021-10-21 | — | — | WO | disclosed |