Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 12/20 | 0.40 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950301 | 0.89 | ATR (0.41) | ATRACVR1SYKAURKAPIM1 | |
| SCHEMBL23925568 | 0.89 | ATR (0.41) | ATRACVR1SYKAURKA | |
| SCHEMBL23950770 | 0.88 | ATR (0.44) | ATRACVR1SYKAURKAPIM1 | |
| SCHEMBL23950297 | 0.88 | ATR (0.44) | ATRACVR1SYKPIM1 | |
| SCHEMBL23950302 | 0.87 | PSD (0.36) | ATRMTOR | |
| SCHEMBL23950547 | 0.84 | SYK (0.43) | ATRACVR1SYKAURKAPIM1 | |
| SCHEMBL23951143 | 0.81 | SYK (0.45) | ATRACVR1SYKAURKAPIM1 | |
| SCHEMBL23951142 | 0.78 | SYK (0.47) | ATRACVR1SYKAURKAPIM1 | |
| SCHEMBL23390302 | 0.76 | CYP2A6 (0.39) | PIM1 | |
| SCHEMBL23390306 | 0.76 | CYP2A6 (0.39) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |