Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925444 | 1.00 | KCNH2 (0.51) | KCNH2ALOX5CHRM1CYP2C9PIM1 | |
| SCHEMBL23925562 | 1.00 | KCNH2 (0.51) | KCNH2ALOX5CHRM1CYP2C9PIM1 | |
| SCHEMBL23925516 | 0.89 | KCNH2 (0.54) | KCNH2ALOX5CHRM1CYP2C9PIM1 | |
| SCHEMBL25463136 | 0.89 | KCNH2 (0.54) | KCNH2ALOX5CHRM1CYP2C9PIM1 | |
| SCHEMBL23950996 | 0.89 | KCNH2 (0.54) | KCNH2ALOX5CHRM1CYP2C9PIM1 | |
| SCHEMBL25463193 | 0.89 | ACVR1 (0.40) | KCNH2PIM1CYP11B1HTR2BHTR6 | |
| SCHEMBL23950995 | 0.87 | HTR2B (0.40) | KCNH2PIM1CYP11B1HTR2BHTR6 | |
| SCHEMBL25463934 | 0.87 | HTR2B (0.40) | KCNH2PIM1CYP11B1HTR2BHTR6 | |
| SCHEMBL23925713 | 0.86 | CYP11B1 (0.39) | KCNH2PIM1CYP11B1HTR2BHTR6 | |
| SCHEMBL23951140 | 0.86 | CYP11B1 (0.39) | KCNH2PIM1CYP11B1HTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |