SCHEMBL2395069

SCHEMBL2395069

CC(C)(C)c1ccc(C(=O)Oc2ccc(C(C)(C)c3ccc(OC(=O)c4ccc(C(C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.75
TDP1 Q9NUW8 2/20 0.75
L3MBTL1 Q9Y468 1/20 0.75
PRSS1 P07477 1/20 0.66
ACR P10323 1/20 0.66
ALDH1A1 P00352 2/20 0.59
THRB P10828 1/20 0.59
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NPSR1 Q6W5P4 2/20 0.53
HSD17B10 Q99714 2/20 0.50
LMNA P02545 1/20 0.50
ALOX15 P16050 1/20 0.50
APEX1 P27695 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
TRPV1 Q8NER1 1/20 0.48
NPC1 O15118 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14062435 0.94 MAPT (0.83) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL2396251 0.94 MAPT (0.83) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL15887454 0.91 MAPT (0.63) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL14062417 0.89 MAPT (0.75) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL14062466 0.89 MAPT (0.75) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL25491844 0.88 TDP1 (0.58) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL10457335 0.88 MAPT (0.58) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL21266478 0.88 MAPT (0.73) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL21681865 0.88 MAPT (0.58) MAPTTDP1L3MBTL1PRSS1ACR
SCHEMBL16775315 0.88 MAPT (0.73) MAPTTDP1L3MBTL1PRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US claimed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885TDP1 3534/4885L3MBTL1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.