Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950733 | 0.77 | CHRM2 (0.44) | CHRM2CHRM1CHRM3 | |
| SCHEMBL24024276 | 0.77 | CHRM2 (0.44) | CHRM2CHRM1CHRM3 | |
| SCHEMBL23926142 | 0.77 | CHRM2 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL25066653 | 0.70 | CHRM2 (0.37) | CHRM2CHRM1CHRM3 | |
| SCHEMBL22737961 | 0.70 | FFAR1 (0.38) | — | |
| SCHEMBL30218180 | 0.69 | GBA2 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL19021611 | 0.69 | — | — | |
| SCHEMBL23006552 | 0.68 | — | — | |
| SCHEMBL26724232 | 0.68 | CHRM3 (0.38) | CHRM3 | |
| SCHEMBL24896835 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211864-A1 | FUSED TRICYCLIC KRAS INHIBITORS | INCYTE CORPORATION (US) | 2021-10-21 | — | — | WO | disclosed |