Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23953572 | 1.00 | HPGD (0.46) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL21257425 | 1.00 | HPGD (0.46) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20064655 | 0.94 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20065450 | 0.92 | KDM4E (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL21257436 | 0.92 | KDM4E (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20065446 | 0.92 | KDM4E (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20064661 | 0.92 | KDM4E (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL20065445 | 0.92 | KDM4E (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL18198610 | 0.91 | HPGD (0.43) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL23953956 | 0.91 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288942-B1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-10-27 | — | — | EP | disclosed |