Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457897 | 0.76 | AKT1 (0.43) | AKT1CAPN1SYKTDP1CA1 | |
| SCHEMBL20729998 | 0.76 | AKT1 (0.42) | AKT1KDM4ESYKMALT1GAA | |
| SCHEMBL31064794 | 0.76 | AKT1 (0.42) | AKT1CAPN1SYKCA1CA2 | |
| SCHEMBL17251637 | 0.73 | AKT1 (0.44) | AKT1KDM4ESYKMALT1GAA | |
| SCHEMBL25457896 | 0.73 | AKT1 (0.44) | AKT1KDM4ESYKMALT1GAA | |
| SCHEMBL19295842 | 0.73 | AKT1 (0.41) | AKT1KDM4ESYKTDP1MALT1 | |
| SCHEMBL15395841 | 0.73 | AKT1 (0.44) | AKT1KDM4ESYKMALT1GAA | |
| SCHEMBL25495314 | 0.73 | AKT1 (0.41) | AKT1KDM4ESYKTDP1MALT1 | |
| SCHEMBL25495453 | 0.72 | AKT1 (0.41) | AKT1KDM4ESYKTDP1MALT1 | |
| SCHEMBL26272998 | 0.72 | AKT1 (0.41) | AKT1KDM4ESYKTDP1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3900742-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | Seagen Inc. (US) | 2021-10-27 | — | — | EP | disclosed |