Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 15/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020804 | 0.85 | CHRNA7 (0.81) | CHRNA7 | |
| SCHEMBL23928851 | 0.85 | CHRNA7 (0.81) | CHRNA7 | |
| SCHEMBL23928863 | 0.84 | CHRNA7 (0.71) | CHRNA7 | |
| SCHEMBL23957101 | 0.81 | CHRNA7 (0.69) | CHRNA7HTR2A | |
| SCHEMBL23957099 | 0.80 | CHRNA7 (0.69) | CHRNA7 | |
| SCHEMBL23957127 | 0.78 | CHRNA7 (0.62) | CHRNA7EPHX2TRPM8HTR2ALMNA | |
| SCHEMBL23957128 | 0.77 | CHRNA7 (1.00) | CHRNA7 | |
| SCHEMBL23957111 | 0.77 | CHRNA7 (0.68) | CHRNA7 | |
| SCHEMBL23957154 | 0.76 | CHRNA7 (0.65) | CHRNA7EPHX2TRPM8 | |
| SCHEMBL26053632 | 0.76 | CHRNA7 (0.73) | CHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330650-A1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330650-A1 | SPIROCHROMANE DERIVATIVES | CHRNA7, CHRM3, ADRB3 | CHRNA7 1/4885EPHX2 1079/4885TRPM8 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.