Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.39 |
| ▸ | FYN | P06241 | 12/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931896 | 0.74 | FYN (0.56) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23932078 | 0.73 | CCNT1 (0.54) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23932068 | 0.73 | CDK5 (0.65) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23932106 | 0.73 | NTRK1 (0.45) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23932223 | 0.72 | CCNT1 (0.50) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23931991 | 0.72 | NTRK1 (0.44) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23931847 | 0.71 | NTRK1 (0.43) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL23931927 | 0.69 | GSK3B (0.42) | NTRK1NTRK3NTRK2MKNK1FYN | |
| SCHEMBL16023624 | 0.68 | MKNK1 (0.39) | NTRK1NTRK3NTRK2MKNK1 | |
| SCHEMBL15254231 | 0.68 | NTRK1 (0.50) | NTRK1NTRK3NTRK2MKNK1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216757-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |