Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16373134 | 0.81 | CYP2D6 (0.39) | CYP2D6CYP2C19KMT2ACYP2C9GRIK1 | |
| SCHEMBL26203718 | 0.79 | CYP2D6 (0.38) | CYP2D6CYP2C19KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL25514818 | 0.77 | CYP2D6 (0.37) | CYP2D6CYP2C19KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL25815757 | 0.76 | KMT2A (0.38) | CYP2D6CYP2C19KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL4807821 | 0.75 | — | — | |
| SCHEMBL24608176 | 0.74 | CYP2C19 (0.39) | CYP2D6CYP2C19KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL11573366 | 0.74 | EPHX1 (0.39) | KMT2AGRIK1GRIK2ALDH1A1MEN1 | |
| SCHEMBL103387 | 0.74 | — | — | |
| SCHEMBL24812862 | 0.73 | KMT2A (0.53) | CYP2D6CYP2C19KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL9967749 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216998-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2021-10-28 | — | — | WO | disclosed |