Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958727 | 1.00 | CFTR (0.37) | CFTRMAPTLMNAFPR2SCN9A | |
| SCHEMBL25686809 | 1.00 | CFTR (0.37) | CFTRMAPTLMNAFPR2SCN9A | |
| SCHEMBL23958674 | 0.85 | CFTR (0.34) | CFTRMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL23958789 | 0.84 | CFTR (0.35) | CFTRLMNAFPR2SCN9AMAPK14 | |
| SCHEMBL25686843 | 0.84 | CFTR (0.35) | CFTRLMNAFPR2SCN9AMAPK14 | |
| SCHEMBL25686838 | 0.84 | CFTR (0.35) | CFTRLMNAFPR2SCN9AMAPK14 | |
| SCHEMBL25686805 | 0.84 | CFTR (0.37) | CFTRMAPTSCN9AALDH1A1PKM | |
| SCHEMBL23958689 | 0.84 | CFTR (0.35) | CFTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL30006775 | 0.84 | CFTR (0.35) | CFTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL23958643 | 0.84 | CFTR (0.35) | CFTRMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |