Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958761 | 0.94 | CFTR (0.35) | CFTRIRAK4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL23958708 | 0.94 | CFTR (0.35) | CFTRIRAK4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL25687421 | 0.89 | CFTR (0.34) | CFTRIRAK4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL30007181 | 0.89 | CFTR (0.34) | CFTRIRAK4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL28909172 | 0.89 | CFTR (0.34) | CFTRIRAK4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL23958706 | 0.85 | CFTR (0.36) | CFTRROCK2ROCK1MAPTCNR2 | |
| SCHEMBL30007924 | 0.85 | CFTR (0.36) | CFTRROCK2ROCK1MAPTCNR2 | |
| SCHEMBL23958644 | 0.85 | CFTR (0.36) | CFTRROCK2ROCK1MAPTCNR2 | |
| SCHEMBL25687411 | 0.85 | CFTR (0.36) | CFTRROCK2ROCK1MAPTCNR2 | |
| SCHEMBL25233772 | 0.85 | CFTR (0.34) | CFTRROCK2ROCK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |