Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.36 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958982 | 0.89 | CFTR (0.33) | CFTRFOXM1SCN9APOLBKMT2A | |
| SCHEMBL25687476 | 0.79 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL23958713 | 0.79 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL30007116 | 0.79 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL25687474 | 0.79 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL25687377 | 0.76 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL30006910 | 0.76 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL25687469 | 0.76 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL28909124 | 0.76 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 | |
| SCHEMBL25687470 | 0.76 | SCN9A (0.38) | CFTRSCN9APOLBKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |