Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25686557 | 1.00 | CFTR (0.37) | CFTRPTGS2TRPV1SCN9APTGS1 | |
| SCHEMBL23958851 | 1.00 | CFTR (0.37) | CFTRPTGS2TRPV1SCN9APTGS1 | |
| SCHEMBL25686632 | 0.90 | CFTR (0.38) | CFTRPTGS2TRPV1SCN9APTGS1 | |
| SCHEMBL25686633 | 0.90 | CFTR (0.38) | CFTRPTGS2TRPV1SCN9APTGS1 | |
| SCHEMBL25687315 | 0.87 | CFTR (0.38) | CFTRADORA2AADORA1 | |
| SCHEMBL23958691 | 0.85 | CFTR (0.38) | CFTRPTGS2TRPV1SCN9A | |
| SCHEMBL23958938 | 0.85 | CFTR (0.38) | CFTRPTGS2PTGS1SMN1; SMN2ADORA2A | |
| SCHEMBL30007210 | 0.85 | CFTR (0.38) | CFTRPTGS2PTGS1SMN1; SMN2ADORA2A | |
| SCHEMBL23958591 | 0.85 | CFTR (0.38) | CFTRPTGS2PTGS1SMN1; SMN2ADORA2A | |
| SCHEMBL25686538 | 0.85 | CFTR (0.38) | CFTRPTGS2PTGS1SMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |