Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687482 | 0.84 | CFTR (0.33) | CFTRARSLC5A7 | |
| SCHEMBL28909136 | 0.84 | CFTR (0.33) | CFTRARSLC5A7 | |
| SCHEMBL30007206 | 0.84 | CFTR (0.33) | CFTRARSLC5A7 | |
| SCHEMBL23905281 | 0.83 | — | — | |
| SCHEMBL30007413 | 0.82 | CFTR (0.34) | CFTRP2RX3P2RX2AR | |
| SCHEMBL23958646 | 0.82 | CFTR (0.34) | CFTRP2RX3P2RX2AR | |
| SCHEMBL25241094 | 0.82 | CFTR (0.34) | CFTRP2RX3P2RX2AR | |
| SCHEMBL25687473 | 0.82 | CFTR (0.34) | CFTRP2RX3P2RX2ARSLC5A7 | |
| SCHEMBL25687485 | 0.82 | CFTR (0.36) | CFTRP2RX3P2RX2AR | |
| SCHEMBL28961080 | 0.80 | CFTR (0.31) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |