Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687466 | 0.82 | SCN9A (0.36) | SCN9AABCB1ACACBACACA | |
| SCHEMBL30007220 | 0.82 | SCN9A (0.36) | SCN9AABCB1ACACBACACA | |
| SCHEMBL25687467 | 0.82 | SCN9A (0.36) | SCN9AABCB1ACACBACACA | |
| SCHEMBL28909130 | 0.82 | SCN9A (0.36) | SCN9AABCB1ACACBACACA | |
| SCHEMBL25687476 | 0.80 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25687377 | 0.80 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30007116 | 0.80 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23958713 | 0.80 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25687474 | 0.80 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30006910 | 0.79 | SCN9A (0.38) | SCN9ATP53ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |