Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391018 | 0.91 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL20419223 | 0.91 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL21456915 | 0.91 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL23664220 | 0.91 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388504 | 0.85 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388565 | 0.85 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL29421227 | 0.85 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388503 | 0.85 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL23664091 | 0.85 | ABL1 (0.64) | ABL1 | |
| SCHEMBL15388213 | 0.84 | ABL1 (0.76) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213380-A1 | SOLID FORM OF PYRAZINE SUBSTITUTED NICOTINAMIDE, AND PREPARATION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |