Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 8/20 | 0.51 |
| ▸ | AKT2 | P31751 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959491 | 0.91 | AKT1 (0.54) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959240 | 0.89 | AKT1 (0.53) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959101 | 0.89 | AKT1 (0.47) | AKT1AKT2KDM4EDHODHROCK2 | |
| SCHEMBL23959492 | 0.88 | AKT1 (0.52) | AKT1AKT2KDM4EROCK2PIM1 | |
| SCHEMBL23959215 | 0.88 | AKT1 (0.49) | AKT1AKT2DHODHROCK2PIM1 | |
| SCHEMBL23959244 | 0.88 | AKT1 (0.51) | AKT1AKT2KDM4EROCK2PIM1 | |
| SCHEMBL23959210 | 0.87 | AKT1 (0.46) | AKT1AKT2KDM4EDHODHROCK2 | |
| SCHEMBL23959207 | 0.87 | AKT1 (0.56) | AKT1AKT2KDM4EROCK2PIM1 | |
| SCHEMBL23959214 | 0.87 | AKT1 (0.45) | AKT1AKT2KDM4EDHODHROCK2 | |
| SCHEMBL23959493 | 0.86 | AKT1 (0.48) | AKT1AKT2DHODHROCK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192901-B2 | Nitrogen-containing heterocyclic organic compound and organic electroluminescent device | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2021-12-07 | — | — | US | disclosed |
| US-20210332066-A1 | NITROGEN-CONTAINING HETEROCYCLIC ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192901-B2 | Nitrogen-containing heterocyclic organic compound and organic electroluminescent device | H1-10, H1-0, OR10J3 | AKT1 1176/4885AKT2 1711/4885KDM4E 2663/4885 |
| US-20210332066-A1 | NITROGEN-CONTAINING HETEROCYCLIC ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | H1-10, H1-0, OR10J3 | AKT1 1176/4885AKT2 1711/4885KDM4E 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.