SCHEMBL23959624

SCHEMBL23959624

Clc1ccc2c(c1)C1(c3ccccc3-2)C2CCC3CC(C2)CC1C3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.41
AKR1A1 P14550 1/20 0.38
AKR1B1 P15121 1/20 0.38
HSD11B1 P28845 3/20 0.33
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
DRD2 P14416 2/20 0.33
CHRM3 P20309 2/20 0.33
DRD1 P21728 2/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
ADRA1A P35348 2/20 0.33
HTR2B P41595 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
BACE1 P56817 1/20 0.33
S100A4 P26447 1/20 0.32
NPY5R Q15761 1/20 0.31
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733681 0.94 PDK2 (0.45) PDK2AKR1A1AKR1B1HSD11B1S100A4
SCHEMBL22780112 0.94 PDK2 (0.45) PDK2AKR1A1AKR1B1HSD11B1S100A4
SCHEMBL23609480 0.87 PDK2 (0.42) PDK2AKR1A1AKR1B1HSD11B1S100A4
SCHEMBL24728354 0.85 PDK2 (0.49) PDK2AKR1A1AKR1B1HSD11B1BACE1
SCHEMBL22797179 0.85 PDK2 (0.49) PDK2AKR1A1AKR1B1HSD11B1BACE1
SCHEMBL24848654 0.85 PDK2 (0.50) PDK2AKR1A1AKR1B1CHRM2CHRM4
SCHEMBL25818648 0.84 PDK2 (0.38) PDK2AKR1A1AKR1B1HSD11B1CHRM2
SCHEMBL25501424 0.84 PDK2 (0.38) PDK2AKR1A1AKR1B1HSD11B1S100A4
SCHEMBL23626029 0.84 PDK2 (0.40) PDK2AKR1A1AKR1B1CHRM2CHRM4
SCHEMBL22787951 0.83 PDK2 (0.50) PDK2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021213109-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 (CN) 2021-10-28 WO disclosed