Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 17/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 14/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 11/20 | 0.44 |
| ▸ | PSMB10 | P40306 | 11/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 11/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 10/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 10/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 10/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 10/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 10/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 10/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 10/20 | 0.44 |
| ▸ | PSMA5 | P28066 | 10/20 | 0.44 |
| ▸ | PSMB4 | P28070 | 10/20 | 0.44 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.44 |
| ▸ | PSMB3 | P49720 | 10/20 | 0.44 |
| ▸ | PSMA6 | P60900 | 10/20 | 0.44 |
| ▸ | PSMA8 | Q8TAA3 | 10/20 | 0.44 |
| ▸ | PSMB7 | Q99436 | 10/20 | 0.44 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515210 | 0.88 | PSMB9 (0.50) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23959833 | 0.86 | PSMB5 (0.64) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23959811 | 0.85 | PSMB5 (0.65) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23959829 | 0.85 | PSMB5 (0.43) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23959831 | 0.84 | PSMB5 (0.43) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23959807 | 0.81 | PSMB5 (0.69) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL23616309 | 0.79 | PSMB8 (0.51) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL25515895 | 0.77 | PSMB5 (0.55) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL25515211 | 0.75 | PSMB5 (0.73) | PSMB5PSMB8PSMB9PSMB10PSMB2 | |
| SCHEMBL19289268 | 0.75 | PSMB8 (0.51) | PSMB5PSMB8PSMB9PSMB10PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159586-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER | 2023-05-25 | — | — | US | disclosed |
| WO-2021216670-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER (US) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159586-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | MAN2B2, NASP, BRDT | PSMB5 1745/4885PSMB8 3073/4885PSMB9 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.