Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 8/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960096 | 1.00 | TMPRSS2 (0.47) | TMPRSS2ACVRL1PIK3CDCDK5CDK5R1 | |
| SCHEMBL23959861 | 0.87 | TMPRSS2 (0.47) | TMPRSS2ACVRL1PIK3CD | |
| SCHEMBL25826835 | 0.87 | TMPRSS2 (0.47) | TMPRSS2ACVRL1PIK3CDCDK5CDK5R1 | |
| SCHEMBL23959872 | 0.87 | TMPRSS2 (0.47) | TMPRSS2ACVRL1PIK3CDCDK5CDK5R1 | |
| SCHEMBL23959859 | 0.87 | TMPRSS2 (0.47) | TMPRSS2ACVRL1PIK3CDCDK5CDK5R1 | |
| SCHEMBL23959862 | 0.87 | TMPRSS2 (0.47) | TMPRSS2ACVRL1 | |
| SCHEMBL23959873 | 0.85 | TMPRSS2 (0.51) | TMPRSS2ACVRL1PIK3CDCDK5CDK5R1 | |
| Gs-441524 SCHEMBL24667691 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ACVRL1CDK5CDK5R1HSPA8 | |
| Gs-441524 SCHEMBL24975226 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ACVRL1CDK5CDK5R1HSPA8 | |
| Gs-441524 SCHEMBL23870459 | 0.82 | TMPRSS2 (0.60) | TMPRSS2ACVRL1CDK5CDK5R1HSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213288-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | 中国科学院上海药物研究所 (CN) | 2021-10-28 | — | — | WO | disclosed |