Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | MTOR | P42345 | 3/20 | 0.54 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038020 | 0.91 | KMT2A (0.62) | EPHX2MTORBAZ1AGRIK1MAPT | |
| SCHEMBL11885104 | 0.86 | EPHX2 (0.51) | EPHX2MTORBAZ1AGRIK1MAPT | |
| SCHEMBL11003408 | 0.80 | EPHX2 (1.00) | EPHX2MTORBAZ1AMAPTCA12 | |
| SCHEMBL28729179 | 0.80 | EPHX2 (1.00) | EPHX2MTORBAZ1AMAPTCA12 | |
| SCHEMBL4922162 | 0.79 | EPHX2 (0.81) | EPHX2MTORBAZ1AGRIK1MAPT | |
| SCHEMBL18037987 | 0.78 | KMT2A (0.63) | EPHX2MAPTKMT2AMEN1HTT | |
| SCHEMBL16540893 | 0.78 | APP (0.51) | EPHX2 | |
| SCHEMBL11885143 | 0.78 | EPHX2 (0.54) | EPHX2MTORBAZ1AGRIK1MAPT | |
| SCHEMBL2393734 | 0.77 | EPHX2 (0.56) | EPHX2MTORBAZ1AMAPTCA12 | |
| SCHEMBL18038056 | 0.77 | KMT2A (0.72) | GRIK1MAPTMAPK14KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| WO-2009048752-A2 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MTOR 1693/4885BAZ1A 1694/4885 |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MTOR 1693/4885BAZ1A 1694/4885 |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MTOR 1693/4885BAZ1A 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.