Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23482534 | 0.88 | PTGS1 (0.52) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL25939244 | 0.88 | PTGS1 (0.52) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL25130218 | 0.88 | PTGS1 (0.52) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL23451312 | 0.88 | PTGS1 (0.52) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL23451319 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL23482804 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL22044568 | 0.78 | PTGS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL24872388 | 0.78 | PTGS1 (0.45) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL24872313 | 0.77 | PTGS1 (0.44) | PTGS1PTGS2AKT1ATM | |
| SCHEMBL24872323 | 0.77 | PTGS1 (0.44) | PTGS1PTGS2AKT1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |