Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671137 | 0.85 | GAA (0.71) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL27432885 | 0.85 | GAA (0.76) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL27432296 | 0.83 | GAA (0.68) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL20467619 | 0.83 | GAA (0.68) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL17183464 | 0.83 | SMN1; SMN2 (1.00) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL21837629 | 0.82 | GAA (0.71) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL28818396 | 0.81 | GAA (0.69) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL22185907 | 0.81 | GAA (0.64) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL20467667 | 0.81 | GAA (0.86) | GAAMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL18416958 | 0.80 | GAA (0.78) | GAAMEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904568-A1 | MUTATED TRNA FOR CODON EXPANSION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-11-03 | — | — | EP | disclosed |