Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | ITK | Q08881 | 4/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL2396584 | 0.89 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2399204 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2399210 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2401283 | 0.78 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2401269 | 0.78 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2402107 | 0.78 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2398651 | 0.78 | PIK3CG (0.56) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2402111 | 0.78 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2398648 | 0.78 | PIK3CG (0.56) | PIK3CDPIK3CGPIK3CAITKLCK | |
| SCHEMBL2396496 | 0.77 | PIK3CG (0.52) | PIK3CDPIK3CGPIK3CAITKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |