SCHEMBL23965824

SCHEMBL23965824

Cc1cc(F)cc(C)c1CNc1cc(C=O)cn2c(C)c(C)nc12

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 20/20 0.50
CYP2C9 P11712 20/20 0.50
CYP2D6 P10635 10/20 0.49
CYP1A2 P05177 7/20 0.49
CYP2C19 P33261 8/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987025 0.87 CYP3A4 (0.52) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL7498693 0.84 CYP3A4 (0.52) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL7502768 0.83 CYP3A4 (0.51) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL31534484 0.82 CYP3A4 (0.50) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL31534499 0.81 CYP3A4 (0.52) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL5257152 0.81 CYP3A4 (0.59) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
Pyrophosphoric Acid SCHEMBL31756907 0.80 CYP3A4 (0.57) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL1813559 0.80 CYP3A4 (0.70) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL31534413 0.79 CYP3A4 (0.50) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19
SCHEMBL7491419 0.78 CYP3A4 (0.54) CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481827-B1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USE THEREOF JEIL PHARMACEUTICAL CO LTD (KR) 2021-11-03 EP disclosed