Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | RAB27A | P51159 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966061 | 0.90 | HRH3 (0.45) | HRH3KCNH2ADRA1AEHMT2EHMT1 | |
| SCHEMBL24211144 | 0.83 | PIK3CB (0.51) | HRH3KCNH2EHMT2EHMT1KDR | |
| SCHEMBL23965998 | 0.82 | PIK3CB (0.51) | HRH3KCNH2EHMT2EHMT1KDR | |
| SCHEMBL23966072 | 0.81 | PIK3CD (0.48) | KDRPIK3CDCHRM2PIK3R1PIK3CA | |
| SCHEMBL23966079 | 0.79 | EPHX2 (0.49) | KDRPIK3CDCHRM2PIK3R1PIK3CA | |
| SCHEMBL23965926 | 0.79 | PIK3CB (0.46) | KDRPIK3CDCHRM2PIK3R1PIK3CA | |
| SCHEMBL22163833 | 0.78 | PIK3CB (0.47) | KCNH2ACHEKDRPIK3CDCHRM2 | |
| SCHEMBL23965924 | 0.76 | PIK3CB (0.51) | KDRPIK3CDCHRM2PIK3R1PIK3CA | |
| SCHEMBL22183656 | 0.76 | PIK3CB (0.51) | KDRPIK3CDCHRM2PIK3R1PIK3CA | |
| SCHEMBL24211172 | 0.76 | PIK3CB (0.49) | HRH3KCNH2ADRA1AKDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904343-A1 | AMINO QUINAZOLINONE, AMINO ISOQUINOLONE DERIVATIVES AND APPLICATION THEREOF | Zhejiang University (CN) | 2021-11-03 | — | — | EP | disclosed |