Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 13/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908881 | 0.88 | S1PR2 (0.78) | S1PR2KCNH2P2RX3CSF1R | |
| SCHEMBL23915484 | 0.88 | S1PR2 (0.68) | S1PR2KCNH2P2RX3CSF1R | |
| SCHEMBL23915483 | 0.77 | S1PR2 (0.85) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908765 | 0.76 | S1PR2 (1.00) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908757 | 0.76 | S1PR2 (1.00) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23914863 | 0.75 | S1PR2 (0.88) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23909078 | 0.74 | S1PR2 (0.86) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908764 | 0.74 | S1PR2 (1.00) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908766 | 0.74 | S1PR2 (1.00) | S1PR2KCNH2P2RX3 | |
| SCHEMBL23908810 | 0.73 | S1PR2 (0.81) | S1PR2KCNH2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |