Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 11/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915331 | 0.86 | S1PR2 (0.55) | S1PR2EGLN1PGK1 | |
| SCHEMBL23914855 | 0.82 | S1PR2 (0.77) | S1PR2 | |
| SCHEMBL23914706 | 0.79 | S1PR2 (0.82) | S1PR2EGLN1 | |
| SCHEMBL23915346 | 0.78 | S1PR2 (0.55) | S1PR2PGK1 | |
| SCHEMBL23915327 | 0.78 | S1PR2 (0.54) | S1PR2EGLN1PGK1 | |
| SCHEMBL23915330 | 0.76 | S1PR2 (0.56) | S1PR2 | |
| SCHEMBL23908751 | 0.76 | S1PR2 (0.67) | S1PR2EGLN1 | |
| SCHEMBL23914843 | 0.75 | S1PR2 (0.54) | S1PR2EGLN1PGK1 | |
| SCHEMBL23966889 | 0.75 | S1PR2 (0.58) | S1PR2EGLN1PGK1 | |
| SCHEMBL23915204 | 0.74 | S1PR2 (0.77) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |