Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908996 | 0.93 | S1PR2 (0.67) | S1PR2PIK3CDPIK3CBABCG2BRS3 | |
| SCHEMBL23908755 | 0.91 | S1PR2 (0.68) | S1PR2PIK3CDPIK3CBABCG2BRS3 | |
| SCHEMBL23908842 | 0.83 | S1PR2 (0.79) | S1PR2GAAMEN1KMT2A | |
| SCHEMBL23908735 | 0.83 | S1PR2 (0.66) | S1PR2PIK3CDPIK3CBRHEBNPC1 | |
| SCHEMBL23908851 | 0.82 | S1PR2 (0.64) | S1PR2IDH1RHEBNPC1RAB9A | |
| SCHEMBL23908912 | 0.81 | S1PR2 (0.80) | S1PR2MEN1KMT2A | |
| SCHEMBL23908835 | 0.81 | S1PR2 (0.66) | S1PR2GAAATMMEN1ALDH1A1 | |
| SCHEMBL23914869 | 0.80 | S1PR2 (0.72) | S1PR2PIK3CDPIK3CBMEN1KMT2A | |
| SCHEMBL23908971 | 0.79 | S1PR2 (0.94) | S1PR2MEN1ALDH1A1KMT2A | |
| SCHEMBL23908959 | 0.79 | S1PR2 (0.80) | S1PR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |